Southern Indiana Vacations from $721

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Your Southern Indiana Vacation

Make planning your next big adventure a breeze with a Southern Indiana vacation package. Whether it's nature, history or something else that draws you here, our packages will help you discover it all. A trip to Southern Indiana wouldn't be complete without exploring some of its leading cities, starting with Louisville. A couple of the most popular attractions here include KFC Yum Center and Kentucky Kingdom. Evansville is another favorite with Southern Indiana travelers. Visitors to this destination enjoy Ford Center and Bally's Evansville Casino. When you're ready to stop daydreaming and start doing, Expedia will help turn your Southern Indiana vacation into a reality.

The Latest Southern Indiana vacation packages

Price found within the past 48 hours. Click for updated prices.
Pillow and Paddock B&B

Pillow and Paddock B&B

Save 100% on your flight
$721
per person
Dec 11 - Dec 14
found 24 hours ago
Roundtrip flight included
Miami (MIA) to Louisville (SDF)
10/10 Exceptional! (52 reviews)
Courteous staff and the room was outstanding. It was our second stay at the inn. Everything is first class. We highly recommend it.

Reviewed on Dec 22, 2025

Hotel Covington Cincinnati Riverfront

Hotel Covington Cincinnati Riverfront

Central Business District
$967
per person
Nov 21 - Nov 27
found 1 day ago
Roundtrip flight included
Boston (BOS) to Cincinnati (CVG)
9.6/10 Exceptional! (1,004 reviews)
The Grady

The Grady

Downtown Louisville
$816
per person
Dec 30 - Jan 3
found 16 hours ago
Roundtrip flight included
New York (LGA) to Louisville (SDF)
9.4/10 Exceptional! (1,011 reviews)
voco The Clair Cincinnati Downtown by IHG

voco The Clair Cincinnati Downtown by IHG

Downtown Cincinnati
$821
per person
Nov 21 - Nov 27
found 1 day ago
Roundtrip flight included
Boston (BOS) to Cincinnati (CVG)
9.2/10 Wonderful! (1,406 reviews)
The staff were so accommodating and allowed me to store my breastmilk in their fridge for hours before I checked in and even after I checked out. The hotel was so clean and cute and the bed was super comfortable. Would definitely stay here again.

Reviewed on Oct 18, 2026

Cincinnati's Fidelity Hotel

Cincinnati's Fidelity Hotel

Downtown Cincinnati
Save 100% on your flight
$991
per person
Dec 30 - Jan 2
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Cincinnati (CVG)
9.8/10 Exceptional! (133 reviews)
This was the most beautiful hotel I’ve ever stayed in. I will be back!

Reviewed on Oct 18, 2026

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Where to stay in Southern Indiana

Find the best Southern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southern Indiana
The entrance to the Kentucky Science Center with a large circular structure in the foreground.

West Main Historic District

Boasting the largest collection of cast iron façades outside New York's SoHo district, this historic area features "Museum Row" with attractions like the Louisville Slugger Museum and Muhammad Ali Center.

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Madison Historic District

If you're spending some time in Madison Historic District, Historic District and Schofield House are top sights worth seeing.

A historic building with a prominent clock tower and dome, surrounded by trees and modern buildings.

Downtown Evansville

2 out of top 10 points of interest in this area

Dive into the cultural hub of Evansville, where you can catch a performance by the Evansville Philharmonic Orchestra at Victory Theatre or explore the Children's Museum of Evansville. Don't miss the LST-325 Museum and Ford Center nearby!

A weathered tower with a metal sign reading "Better By Far" and a metal structure with the number "3" on top.

California

If you're spending some time in California, Ohio River Valley and Union Station are top sights worth seeing.

A bridge with a metal truss structure and a highway with vehicles.

Portland

While visiting Portland, you might make a stop by sights like Portland Museum and Lannan Park Trailhead.

Stay near popular Southern Indiana attractions

A river with a bridge, a stadium, and modern buildings.

KFC Yum Center

8.8/10 (1,621 reviews)
This waterfront arena hosts Louisville's premier sporting events and world-class concerts with 22,000 seats. Arrive early to explore downtown's culinary scene before experiencing the vibrant atmosphere inside.
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A water slide with a yellow and green inflatable raft carrying three people.
Photo by Indiana Office of Tourism Development

Holiday World and Splashin' Safari

9.4/10 (294 reviews)
Holiday World features themed holiday areas with thrilling coasters and water attractions. Enjoy complimentary soft drinks and sunscreen while experiencing the world's longest water coaster, Wildebeest.
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A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)
Step inside the world's only Louisville Slugger factory where baseball history comes alive. Watch craftsmen transform raw wood into iconic bats, then hold the same models used by legends like Babe Ruth and Derek Jeter.
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A city street with a large building labeled "FOURTH STREET" and a neon sign for "JIM BEAM."
Photo by Nura Mirzaliyeva

Fourth Street Live!

8.4/10 (2,560 reviews)
Louisville's premier entertainment district offers a vibrant mix of restaurants, bars, and live music venues. Savor diverse culinary experiences and dynamic nightlife in this pedestrian-friendly downtown hub.
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A wooden barrel room with barrels lined up on both sides and a wooden floor.

Whiskey Row

9.2/10 (11 reviews)
Find out about the history of Louisville when you spend time at Whiskey Row. Attend a sporting event or simply enjoy the lively bars while you're in the area.
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Kentucky International Convention Center

8.4/10 (763 reviews)
Downtown Louisville's premier venue, KICC impresses with its modern glass design and light-filled spaces. Attend conventions, trade shows, and exhibitions in this state-of-the-art facility at the heart of the city.
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Bally's Evansville Casino

8.0/10 (505 reviews)
Indiana's first casino offers scenic Ohio River views alongside a vibrant gaming experience. Enjoy upscale dining at Cavanaugh's while watching the river flow past your table.
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Louisville Palace

8.2/10 (488 reviews)
You can get tickets for a performance at Louisville Palace on your trip to Louisville. Experience the area's acclaimed theater scene or attend a sporting event.
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Southern Indiana Hotel Deals

Radisson Hotel Louisville North

Radisson Hotel Louisville North

505 Marriott Drive Clarksville IN
Fully refundable
$67 nightly
$75 total
Nov 19 - Nov 20
Total with taxes and fees
Radisson Hotel Louisville North
Derby Hotel & Suites

Derby Hotel & Suites

505 K Marriot Dr Clarksville IN
Fully refundableReserve now, pay when you stay
$54 nightly
$61 total
Oct 28 - Oct 29
Total with taxes and fees
Derby Hotel & Suites
Santas Lodge and Resort

Santas Lodge and Resort

91 W CHRISTMAS BLVD Santa Claus IN
Fully refundableReserve now, pay when you stay
$101 nightly
$113 total
Oct 20 - Oct 21
Total with taxes and fees
8/10 Very Good! (463 reviews)
"Very clean place only complaint Is no fridge or microwave in rooms. Area night life none restaurants close at 8 on Fridays"

Reviewed on Oct 19, 2026

Santas Lodge and Resort
See all 1,631 properties in Southern Indiana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Southern Indiana Vacation Packages

Things to do near Southern Indiana

Southern Indiana offers a delightful blend of outdoor adventures, picturesque scenery, and romantic getaways. Enjoy fun festivals, explore quirky roadside attractions, and visit popular tourism sites. You can indulge in body treatments or splash around at a local water park, making it a perfect destination for relaxation and excitement. Whether you're seeking a quiet retreat or thrilling activities, Southern Indiana has something for everyone.

Shopping

Discover the charming Jasper City Mill, located 10 miles from Southern Indiana, offering unique gifts and local crafts. Just 19 miles away, Antique Shak features a delightful selection of vintage treasures and collectibles, perfect for finding that special souvenir to remember your trip.

Recreation

Sultan's Run Golf Course offers a fantastic golfing experience with its scenic landscapes and challenging holes, perfect for outdoor enthusiasts. Meanwhile, Jim Yellig Park provides a tranquil setting for relaxation and wellness activities, allowing visitors to unwind amid nature. Jasper Municipal Golf Course also invites sports lovers to enjoy its beautiful fairways.

Adventure

The Ray Yellig Memorial Trail, located 21 miles from Southern Indiana, offers an exhilarating hiking experience. Immerse yourself in the breathtaking scenery as you traverse diverse landscapes, perfect for outdoor enthusiasts seeking adventure and a connection with nature.

Nightlife

Experience the vibrant nightlife of Southern Indiana at the lively River City Casino, where gaming and entertainment blend seamlessly. For a laid-back vibe, check out a local brewery like New Albanian Brewing Co., offering craft beers and a cozy atmosphere perfect for unwinding after a day of exploration.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Southern Indiana

Southern Indiana is perfect for outdoor and romantic getaways, offering a variety of attractions such as urban parks, visitor centers, and arts centers. Travelers can enjoy cultural experiences, family activities, and scenic views. Be sure to explore local tourist destinations and attractions to fully appreciate the charm of this region.

  • Dubois County Visitors Center: Located 9 miles from Southern Indiana, this center offers a gateway to adventure with its outdoor activities perfect for families. Explore local attractions, get travel tips, and enjoy the warm hospitality that embodies the spirit of Dubois County.
  • Thyen-Clark Cultural Center: Situated 10 miles away, this arts center is a cultural gem showcasing local art and performances. Experience the vibrant community through various exhibitions and events that celebrate the rich artistic heritage of the region.
  • St Joseph's Church: Just 9 miles from Southern Indiana, this historic church is not only a place of worship but also a stunning architectural landmark. Its serene atmosphere and beautiful design invite visitors to reflect and appreciate its cultural significance.

Best time to go to Southern Indiana

The best time to visit Southern Indiana is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are moderately high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are moderately low and weather is mostly cloudy with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January33.1°F (0.6000000000000001°C)Light RainMostly CloudyModerately LowSlightly Low
February36.1°F (2.3000000000000003°C)Light RainMostly CloudyModerately LowSlightly Low
March46.2°F (7.9°C)Light RainMostly CloudyAverageSlightly Low
April55.8°F (13.2°C)Light RainMostly SunnyAverageAverage
May64.9°F (18.3°C)Light RainMostly SunnyAverageAverage
June74.3°F (23.5°C)Light RainMostly SunnyModerately HighSlightly High
July77.2°F (25.1°C)Light RainMostly SunnyModerately HighSlightly High
August75.9°F (24.4°C)Light RainMostly SunnyModerately HighSlightly High
September70.0°F (21.1°C)Light RainMostly SunnyAverageAverage
October58.1°F (14.5°C)Light RainMostly SunnyAverageAverage
November45.9°F (7.7°C)Light RainMostly SunnyAverageAverage
December37.8°F (3.2°C)Light RainMostly CloudyModerately LowAverage

Tips to save on your trip to Southern Indiana

  • Combine your flights, hotels and car rentals on Expedia—bundling can result in significant savings.
  • Consider traveling to Southern Indiana during the low season (January to March) for more affordable options.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Southern Indiana Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Cincinnati - Northern Kentucky Intl. Airport (CVG)

More vacations you might like

Frequently asked questions

How do vacation package prices compare across popular destinations in Southern Indiana?
Clarksville typically offers a lower price for a weekend Southern Indiana vacation package compared to Evansville.*Package prices shown are the average total cost per adult across Expedia bookings over the past year and may change depending on availability, dates, and demand.
How can I save money on a Southern Indiana vacation package?
When you bundle, you can save up to 30%*. To save money on a Southern Indiana package, consider traveling during the quieter months or be flexible with your dates to find more options. Bundling your flights and hotel together often unlocks savings compared to booking separately. *Members only. Savings vary.
Which destinations in Southern Indiana offer the best-value vacation package deals?
Clarksville and Evansville are some of the top destinations for cheap Southern Indiana vacation package deals. For an affordable trip, Clarksville is often among the most budget-friendly options, with package prices starting around $500 per adult. For notable bundle savings, Evansville is often among the best options, with flight-and-hotel bundles saving around $30 per adult.Browse cheap vacation packages in Southern Indiana on Expedia to compare current deals.*Package prices shown are the average total cost per adult across Expedia bookings over the past year and may change depending on availability, dates, and demand.
When is the best time to visit the top destinations in Southern Indiana?
The best time for a Southern Indiana vacation package depends on which destination you choose.Evansville is busiest in April and June. April sees highs around 66°F, while June is warmer with highs around 84°F. If you'd prefer fewer crowds, January is quieter, with highs around 40°F.Clarksville experiences its highest demand in September and April. September offers highs around 81°F, and April is cooler with highs around 66°F. For a quieter trip, January is a good option, with highs around 40°F.New Albany also sees peak visitor numbers in September and April. September highs are around 81°F, and April highs are around 66°F. If you're looking to avoid the busiest times, January is quieter, with highs around 40°F.
What package types are available across the top destinations in Southern Indiana?
Southern Indiana vacation packages offer diverse travel styles across its popular cities like Evansville, Clarksville, and French Lick:
  • Budget: In Evansville, options like Howard Johnson by Wyndham Evansville East, rated 7.6 out of 10 by travelers, provide free breakfast and an outdoor pool. Clarksville also features budget-friendly stays such as Radisson Hotel Louisville North, which includes free breakfast and both indoor and outdoor pools.
  • Family: For families, DoubleTree by Hilton Evansville, a 4-star hotel rated 7.8 out of 10 by travelers, offers family rooms and an outdoor pool, with travelers often recommending its convenient location and spacious rooms. In Clarksville, Radisson Hotel Louisville North provides both indoor and outdoor pools, and travelers frequently praise its fantastic staff and amazing food.
  • Romantic: French Lick, known for romantic getaways, offers stays like Valley Inn and Suites, rated 8.5 out of 10 by travelers, featuring an outdoor pool and free WiFi, with travelers highlighting its spotless overall condition and modern rooms.
  • Breakfast-Included: Drury Inn & Suites Evansville East, rated 9 out of 10 by travelers, is a strong choice in Evansville for its free breakfast, hot tub, and indoor pool, with travelers often noting the good breakfast and nice rooms. In Clarksville, Home2 Suites by Hilton Clarksville Louisville North, rated 7.8 out of 10 by travelers, also includes free breakfast and kitchenettes, with travelers praising the amazing staff and great breakfast.
  • Pet-Friendly: Garner Hotel Evansville East by IHG, rated 8.7 out of 10 by travelers, welcomes pets and offers an outdoor pool and free breakfast, with its great location and value often highlighted. Home2 Suites by Hilton Clarksville Louisville North, rated 7.8 out of 10 by travelers, is another pet-friendly option in Clarksville, providing kitchenettes and free breakfast, and travelers frequently mention the great breakfast and amazing staff.
Which destinations should I consider for a Southern Indiana vacation?
When planning a Southern Indiana vacation, your choice of destination can depend on your preferred travel style:
  • Evansville: A popular package base, this city is ideal for families and those seeking entertainment options, outdoor activities, and a mix of urban and romantic experiences.
  • Clarksville: Another well-established package base, Clarksville is great for family-friendly attractions and travelers interested in business travel, outdoor activities, and city life.
  • French Lick: For a romantic getaway or a trip focused on scenic views and adventure activities, French Lick offers a charming setting with plenty of outdoor opportunities.
  • New Albany: This city provides a good range of lodging choices and is well-suited for family-friendly attractions, outdoor activities, and business travel.
Is Southern Indiana better suited for a beach vacation or a cultural trip?
Southern Indiana is primarily an outdoor and nature destination, known for its scenic views and adventure activities. Travelers can explore numerous state parks like Turkey Run State Park and Shades State Park, or enjoy water activities at Lake Malone.The region does offer cultural and urban attractions, particularly in its cities. Evansville, for example, is known for entertainment options at venues like the Ford Center and Old National Events Plaza. Clarksville also features city attractions such as the Kentucky International Convention Center, alongside its outdoor offerings.Overall, a Southern Indiana vacation is best suited for those seeking outdoor adventures and natural beauty, with opportunities to experience local culture and entertainment in its towns and cities.
Which airports serve the main destinations in Southern Indiana?
For a Southern Indiana vacation, several airports provide convenient access to the region's destinations. Indianapolis International Airport (IND) serves Indianapolis, Indiana, offering a major gateway to the northern part of Southern Indiana. Louisville International Airport (SDF) in Louisville, Kentucky, is a key option for destinations like Clarksville, Jeffersonville, and New Albany, which are just across the Ohio River. Additionally, Evansville Regional Airport (EVV) directly serves the city of Evansville and its surrounding areas.
What are the top things to do across the destinations in Southern Indiana?
A Southern Indiana vacation offers a variety of experiences across its distinct destinations:Browse and book things to do in Southern Indiana on Expedia.
Are there family vacation packages in Southern Indiana with kid-friendly amenities?
Southern Indiana vacation packages offer several family-friendly options with amenities designed for a comfortable stay:
  • Home2 Suites by Hilton Evansville: Rated 8.7 out of 10 by travelers, this hotel in Evansville provides spacious family rooms and kitchenettes, making it convenient for preparing snacks and meals. Travelers frequently highlight the spacious rooms and great pool.
  • Hilton Garden Inn Jeffersonville Louisville North: In Jeffersonville, this hotel, rated 8.6 out of 10 by travelers, features family rooms and a restaurant, with travelers often noting the good rooms and nice facilities.
  • Hampton Inn Evansville: Also in Evansville, this hotel, rated 8.2 out of 10 by travelers, offers an indoor pool and family rooms, and travelers praise its spacious rooms and good breakfast.
When should I book vacation packages for the top destinations in Southern Indiana?
Booking times for Southern Indiana vacation packages vary by destination, with most travelers booking around 2 to 3 weeks before departure.Travelers tend to book Southern Indiana trips most often in May, and from July to October. If you're planning a spontaneous getaway, Expedia also offers last-minute Southern Indiana vacation packages.
How many days do you need for a Southern Indiana vacation?
Most Southern Indiana vacation packages last around 2 to 3 days, but the ideal trip length depends on where you're going and what you'd like to experience.Evansville, primarily known for family-friendly attractions and entertainment options, is well-suited for a trip of around 2 days. Weekend trips are most popular, though week-long stays are also common, allowing time to explore places like the Ford Center.Clarksville, also offering family-friendly attractions and outdoor activities, typically sees trips of around 3 days. Weekend trips are the most common choice, with week-long stays also popular, providing enough time to visit the Kentucky Exposition Center.
Can I change or cancel my Southern Indiana vacation package if my plans change?
Yes, you can cancel your vacation package via your itinerary page on Expedia or by contacting customer service. Remember that some packages are fully refundable, but the details vary based on each unique booking. A fully refundable package may depend on how far out from the travel dates you're canceling and what airline you are traveling with.
Do One Key members get extra savings when booking Southern Indiana vacation packages?
Yes, members who join our free One Key™ travel rewards program can instantly unlock additional savings and save 10% or more on over 500,000 stays worldwide with Member Prices and over 1 million car rentals.
Does Expedia offer Book Now, Pay Later Southern Indiana vacation packages?
Yes, with Expedia's Book Now, Pay Later option, powered by Affirm, you can spread the cost of your Southern Indiana vacation over 3, 6, or 12 months. With no late payment fees or hidden costs, it's easy to secure your ideal vacation package as soon as you spot it.
How do I find last-minute vacation packages to Southern Indiana?
To find last-minute vacation packages to Southern Indiana, explore the last-minute deals section for the latest package offers, including flights, departing in the coming weeks. Being flexible with your travel dates and hotel preferences can help you secure the best prices.
How does free cancellation work on Southern Indiana vacation packages?
Free cancellation on a Southern Indiana vacation package depends on the specific hotel and rate combination you book. Many bookings allow free cancellation up to a stated deadline (often a few days before travel) where eligible. Read the cancellation terms carefully when reviewing the package, and visit Expedia help center for further details.
Is it cheaper to book a Southern Indiana vacation as a package or separately?
An Expedia vacation package could land you great savings when compared to arranging flights and hotels separately. Better still, you can tailor your Southern Indiana getaway to match your exact preference. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
Why should I book my Southern Indiana vacation package with Expedia?
Booking your vacation package on Expedia makes it easier to get more out of your trip from the start. With a wide choice of hotels, you can compare prices, reviews and amenities all in one place, then bundle your hotel with flights which could help you save even more. Flexible booking options on selected stays also make it easier to plan with confidence.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.